Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil. This includes nitrates, like nitroglycerin, used to treat angina. Combining Sildenafil with nitrates can cause a dangerous drop in blood pressure.
Alpha-blockers, prescribed for high blood pressure or prostate problems, can also interact with Sildenafil, potentially causing dizziness or fainting. Your doctor might adjust your dosages or suggest alternatives.
Certain antifungal medications, like ketoconazole and itraconazole, can increase Sildenafil levels in your body, potentially leading to side effects. Similarly, some antibiotics and HIV protease inhibitors may interact.
Avoid grapefruit juice while taking Sildenafil. Grapefruit can increase Sildenafil levels, increasing the risk of side effects.
CYP3A4 inhibitors are a class of drugs that can interact significantly with Sildenafil. Your doctor can help assess any potential risks.
Never self-medicate. Discuss any concerns with your healthcare provider before making any changes to your medication regimen. They can assess your specific situation and provide personalized advice.


