Topiramate, even at a 100mg dose, can cause various side effects. Many are mild and temporary, but some require medical attention. Understanding these potential effects allows for proactive management and informed discussion with your doctor.
Common Side Effects
- Drowsiness: This is frequently reported. Consider avoiding driving or operating machinery until you know how topiramate affects you. Weight loss: Reduced appetite is common. Maintain a healthy diet and discuss any significant weight changes with your physician. Tingling sensations (paresthesia): This usually affects the extremities (hands and feet). Cognitive changes: Some individuals experience difficulty with concentration or memory. Gastrointestinal issues: Nausea, diarrhea, or constipation can occur.
Less Common but Serious Side Effects
While less frequent, these side effects warrant immediate medical attention:
Kidney stones: Increased risk is associated with topiramate use. Drink plenty of fluids to help prevent this. Metabolic acidosis: A dangerous imbalance of acid and base in your blood. Symptoms may include fatigue, nausea, and shortness of breath. Severe allergic reactions: These are rare but can be life-threatening. Seek immediate medical help if you experience hives, swelling, or difficulty breathing. Suicidal thoughts or behaviors: Topiramate, like other anticonvulsants, carries a small increased risk of these. Report any concerning thoughts or changes in mood immediately.
Managing Side Effects
Your doctor can adjust your dosage or suggest strategies to minimize side effects. Open communication is key. Don’t hesitate to report any concerns, even minor ones, to your healthcare provider. They can help you manage these and ensure you receive the most benefit from your treatment.


