Short-term prednisone treatment offers significant benefits, but it’s crucial to understand potential side effects and how to minimize them. Many side effects are dose-dependent and usually disappear once you stop taking the medication.
Common Side Effects
- Increased appetite and weight gain: Choose healthy, nutrient-rich foods. Focus on portion control. Regular exercise helps counter weight gain. Mood changes (irritability, anxiety, insomnia): Maintain a regular sleep schedule. Engage in relaxing activities like yoga or meditation. Talk to your doctor if mood changes are severe. Increased blood sugar: Monitor your blood sugar regularly, especially if you have diabetes. Your doctor may adjust your diabetes medication. Fluid retention (swelling): Reduce sodium intake. Drink plenty of water. Elevate your legs when resting. Increased blood pressure: Monitor your blood pressure. Your doctor may need to adjust your blood pressure medication. Acne and skin thinning: Gentle skin care is recommended. Avoid harsh soaps and scrubbing. Use a sunscreen with a high SPF. Headaches: Stay hydrated. Over-the-counter pain relievers may help, but consult your doctor before use, particularly if you are also taking other medication.
Less Common but Serious Side Effects
Osteoporosis: Maintain adequate calcium and vitamin D intake. Weight-bearing exercises are beneficial. Your doctor might discuss bone density monitoring. Increased risk of infection: Practice good hygiene. Avoid contact with sick individuals. Report any signs of infection to your doctor immediately. Gastrointestinal issues (ulcers, gastritis): Take prednisone with food. Your doctor may prescribe a medication to protect your stomach lining. Muscle weakness: Consult with your doctor or physical therapist about appropriate exercise and activities to maintain muscle strength.
Remember to report any concerning symptoms to your doctor promptly. They can provide personalized advice and adjust your treatment plan as needed. Open communication is key to a safe and effective prednisone treatment experience.


