Accutane, or isotretinoin, primarily works by reducing sebum production, a key factor in acne development. It achieves this by binding to retinoic acid receptors in sebaceous glands, decreasing the size of these glands and thus lowering oil output. This targeted action explains why Accutane is so effective against severe acne.
Weight changes are a reported side effect, though not consistently experienced by all patients. Some individuals may experience slight weight gain, while others report weight loss. The mechanism behind these changes isn’t fully understood, but several factors might play a role. Changes in appetite, often decreased, can contribute to weight loss. Conversely, increased fatigue, another potential side effect, might lead to decreased physical activity and thus, potential weight gain.
Increased triglyceride levels, a lipid in the blood, are also a potential side effect of isotretinoin. Elevated triglycerides can, in some cases, be related to weight gain, though the link isn’t always direct. Regular blood tests are recommended to monitor lipid levels during treatment. Maintaining a healthy diet and regular exercise throughout your treatment course can help mitigate potential weight fluctuations.
Individual responses vary significantly. Your doctor can discuss specific risk factors and monitor your progress to address any concerns about weight changes during your Accutane treatment.
