Contact your doctor immediately if you experience any of the following while taking phenazopyridine:
| Severe allergic reaction (e. g., difficulty breathing, swelling of the face, lips, tongue, or throat) | Seek immediate emergency medical care. This is a life-threatening situation. |
| Jaundice (yellowing of the skin or eyes) | Contact your doctor; this may indicate liver problems. |
| Unusual bleeding or bruising | Contact your doctor; this could signify a blood disorder. |
| Persistent or worsening pain despite taking phenazopyridine | Contact your doctor; this may suggest the infection isn’t responding to treatment. |
| Dark urine or pale stools | Contact your doctor; these are signs of potential liver or gallbladder issues. |
| High fever (over 101°F or 38.3°C) | Contact your doctor; this indicates a severe infection requiring further attention. |
| Symptoms persisting beyond two days after initiating treatment | Contact your doctor; this suggests the infection might require a different approach. |
| Metallic taste in mouth lasting longer than expected | Contact your doctor; this is an unusual side effect requiring evaluation. |
Always inform your doctor about all medications you are taking, including over-the-counter drugs and supplements, before starting phenazopyridine or any other medication.
