Contact your doctor immediately if you experience severe side effects during treatment. This includes but is not limited to: severe allergic reactions (rash, swelling, difficulty breathing), persistent nausea or vomiting, severe abdominal pain, diarrhea that lasts more than a few days, or signs of liver problems (yellowing of skin or eyes, dark urine, light-colored stools).
When to Follow Up
Schedule a follow-up appointment with your doctor after completing the prescribed course of doxycycline to assess the eradication of H. pylori. This usually involves a breath test or stool antigen test.
- Don’t assume the infection is gone without confirmation. Retreatment may be necessary depending on test results.
Reasons for Early Contact
Seek medical attention sooner rather than later if:
Your symptoms worsen during treatment. You experience new or unexplained symptoms. You have pre-existing health conditions that might interact with doxycycline. You are pregnant, breastfeeding, or planning to become pregnant. You are taking other medications that may interact with doxycycline. Provide your doctor with a complete list of all medications, supplements, and herbal remedies.
Proactive communication with your healthcare provider ensures the safest and most effective treatment for H. pylori infection.


