What is Sucralfate and How Does it Work?

Sucralfate is a medication used to treat duodenal ulcers and other gastrointestinal issues causing heartburn and acid reflux. It works by forming a protective barrier over ulcers and irritated areas in your stomach and duodenum.

How Sucralfate Creates a Protective Layer

Sucralfate interacts with stomach acid, transforming into a thick, sticky paste that adheres to the ulcer site. This paste acts as a shield, preventing further acid damage and promoting healing. The protective layer isn’t just a physical barrier; it also enhances the natural healing process by binding to proteins that promote ulcer repair.

This unique mechanism allows sucralfate to provide targeted relief, focusing its action where it’s needed most. Unlike some medications, it doesn’t neutralize stomach acid directly; instead, it creates a physical barrier and supports the body’s own healing processes. This barrier remains in place for several hours, providing sustained protection from acid exposure.