Sildenafil Pfizer 100mg is a brand-name prescription medication containing sildenafil citrate, used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, facilitating an erection when sexually stimulated.
Understanding the Mechanism
Sildenafil inhibits a specific enzyme called phosphodiesterase-5 (PDE5). PDE5 normally breaks down a chemical called cyclic GMP, which is crucial for achieving and maintaining an erection. By blocking PDE5, sildenafil allows cyclic GMP levels to rise, resulting in increased blood flow to the penis.
Dosage and Administration
The typical starting dose is 50mg, taken as needed, about an hour before sexual activity. Your doctor may adjust the dose to 100mg or 25mg based on your response and individual needs. Never exceed the prescribed dose.
Important Considerations
Sildenafil interacts with certain medications, notably nitrates. Combining them can cause a dangerous drop in blood pressure. Consult your doctor about any other medications you are taking. Side effects, though generally mild, include headaches, flushing, and nasal congestion. Severe side effects are rare but warrant immediate medical attention.
Sildenafil and Other ED Treatments
| Sildenafil (Viagra) | PDE5 inhibition | Oral |
| Tadalafil (Cialis) | PDE5 inhibition | Oral |
| Vardenafil (Levitra) | PDE5 inhibition | Oral |
When to Consult a Doctor
Always consult a healthcare professional before starting any ED treatment. They can assess your overall health, rule out underlying conditions, and determine the most appropriate treatment plan for you. This information is for educational purposes only and does not replace professional medical advice.
