Viagra (sildenafil) primarily works by inhibiting phosphodiesterase-5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP). Increased cGMP levels relax blood vessels in the penis, leading to improved blood flow and erectile function. This mechanism, however, isn’t limited to the penis.
PDE5 is present throughout the body, including the digestive tract. Consequently, Viagra’s action can impact blood vessels in the stomach and esophagus. This can manifest as heartburn or acid reflux, due to increased blood flow in these areas, potentially relaxing the lower esophageal sphincter and allowing stomach acid to reflux.
The incidence of heartburn as a side effect varies, but it’s a known possibility. If you experience heartburn after taking Viagra, consider taking it with food to reduce stomach irritation. Over-the-counter antacids might provide temporary relief. However, persistent or severe heartburn warrants consulting a doctor.
Other potential digestive side effects, though less common, include nausea, diarrhea, and abdominal pain. These are often mild and transient. Always report any unusual or persistent digestive symptoms to your physician. They can determine if the symptoms are related to Viagra or another cause.
Remember that individual responses to medication differ. What works for one person may not work for another. Open communication with your healthcare provider is key to managing any side effects effectively.
