Tadalista contains Tadalafil, a phosphodiesterase-5 (PDE5) inhibitor. This means it works by increasing blood flow to the penis. Specifically, Tadalafil blocks the PDE5 enzyme, which normally breaks down cyclic guanosine monophosphate (cGMP). Higher cGMP levels relax the muscles in the blood vessels of the penis, allowing more blood to flow in, leading to an erection.
Pharmacokinetics of Tadalafil
Tadalafil’s effects typically begin within 30 minutes and can last up to 36 hours. Absorption is improved when taken on an empty stomach. The drug is primarily metabolized by the liver and excreted through the kidneys. Dosage should be adjusted based on individual factors and physician recommendations. It’s important to note individual responses may vary.
Considerations Before Use
Tadalista is not suitable for everyone. Men with certain heart conditions, low blood pressure, or those taking specific medications, such as nitrates, should avoid it. Always consult a doctor before using Tadalista to determine its suitability and appropriate dosage. Discuss potential side effects, which can include headache, flushing, and indigestion.
