Prednisone, a corticosteroid, directly impacts your lymphocyte count. It reduces the number of lymphocytes in your blood by inhibiting their production and promoting their death (apoptosis).
This decrease is typically dose-dependent; higher doses lead to a more significant drop in lymphocyte levels. The effect is usually seen within days of starting prednisone. Different lymphocyte subsets (like T cells and B cells) are affected differently, but all experience suppression to some degree.
This suppression is temporary. Your lymphocyte count usually recovers after you stop taking prednisone. The recovery timeline varies depending on factors like the dose and duration of prednisone treatment, your overall health, and individual responses.
Low lymphocyte counts caused by prednisone increase your susceptibility to infections. Regular blood tests monitor your lymphocyte levels during prednisone treatment. Your doctor might adjust your dose or prescribe other medications to manage this risk. Maintaining good hygiene and avoiding contact with sick individuals is also crucial.
Always discuss any concerns about low lymphocyte counts with your doctor. They can assess your individual situation and provide tailored advice and treatment strategies.
