Ciprofloxacin targets bacterial DNA replication. It achieves this by inhibiting two key enzymes: DNA gyrase and topoisomerase IV.
DNA gyrase is crucial for unwinding the supercoiled DNA, allowing replication to begin. Topoisomerase IV helps separate replicated DNA strands, allowing daughter cells to divide. Ciprofloxacin blocks these enzymes, effectively halting bacterial reproduction.
This inhibition is specific to bacterial enzymes; human cells lack these enzymes, minimizing the risk of human cell damage. However, individual reactions vary.
| DNA Gyrase | Unwinds supercoiled DNA | Inhibits unwinding, stopping replication |
| Topoisomerase IV | Separates replicated DNA strands | Prevents strand separation, halting cell division |
The bactericidal action of ciprofloxacin means it directly kills bacteria, unlike bacteriostatic drugs that only slow bacterial growth. This difference impacts treatment duration and effectiveness.
Remember to consult a healthcare professional for any health concerns or before making any decisions related to your health or treatment. This information is for educational purposes only and does not constitute medical advice.
