Monitor your INR more frequently. Consider daily or every-other-day testing while on prednisone, especially during the initial phase of treatment or dosage changes. Your doctor can help determine the appropriate monitoring schedule based on your individual needs and response.
Communicate closely with your healthcare provider. Report any significant changes in your INR, symptoms of bleeding or clotting, or changes in your prednisone dosage immediately. Proactive communication is key.
Adjust your warfarin dose as needed. Your doctor will likely adjust your warfarin dose based on your INR results. Be prepared for potential dose adjustments – this is a common part of managing this interaction.
Consider alternative anticoagulants. In some cases, a direct oral anticoagulant (DOAC) might be a safer option than warfarin when taking prednisone, as DOACs are less susceptible to these interactions. Discuss this possibility with your physician.
Maintain a consistent diet and medication schedule. Consistent intake of vitamin K, found in leafy green vegetables, can affect INR. Maintain a regular schedule for taking both your prednisone and warfarin.
Avoid alcohol and other medications that interact with warfarin. Alcohol and several other medications can interfere with warfarin’s effectiveness and increase the risk of bleeding or clotting. Consult your doctor or pharmacist about potential interactions.


