Both Skelaxin (metaxalone) and Flexeril (cyclobenzaprine) carry potential side effects, but their profiles differ. Skelaxin commonly causes drowsiness, dizziness, and nausea. Less frequent but still possible are headache, lightheadedness, and vomiting. Some individuals experience blurred vision or weakness.
Flexeril’s side effect profile overlaps somewhat, including drowsiness, dizziness, and dry mouth. However, Flexeril more frequently causes constipation and can also lead to increased heart rate and blood pressure. It’s also associated with more instances of blurred vision than Skelaxin.
Important Note: This information is for comparison only and does not substitute professional medical advice. Always discuss potential side effects with your doctor before starting either medication. They can assess your individual risk factors and help you make an informed decision. Report any concerning side effects immediately.
Allergic reactions, though rare, are possible with both drugs. Symptoms might include rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience these.
Consider your personal tolerance for specific side effects. If you’re highly sensitive to drowsiness, for example, Skelaxin’s slightly higher incidence might be a greater concern. Likewise, individuals with pre-existing digestive issues may find Flexeril’s constipation risk problematic.


