Always inform your doctor about all medications you’re taking, including over-the-counter drugs, supplements, and herbal remedies. Prednisone interacts with many medications, potentially increasing or decreasing their effectiveness or causing adverse effects.
Blood thinners (anticoagulants): Prednisone can reduce the effectiveness of blood thinners like warfarin, increasing your risk of blood clots. Your doctor may need to adjust your dosage of either medication.
Nonsteroidal anti-inflammatory drugs (NSAIDs): Combining Prednisone with NSAIDs (like ibuprofen or naproxen) increases your risk of stomach ulcers and bleeding. Careful monitoring and potentially lower dosages are necessary.
Diabetes medications: Prednisone can raise blood sugar levels, potentially interfering with the effectiveness of your diabetes medication. Close blood sugar monitoring and possible adjustments to your diabetes treatment plan are needed.
Potassium-wasting diuretics: Prednisone can worsen the potassium-lowering effect of certain diuretics. This can lead to dangerously low potassium levels. Regular potassium level checks are important.
Vaccines: Prednisone may weaken your immune response to vaccines. Discuss vaccination timing with your healthcare provider.
Other interactions: Prednisone can also affect medications for heart conditions, mental health, infections, and bone health. Thorough communication with your doctor ensures safe and effective treatment. Never stop taking Prednisone or alter the dose without consulting your physician.
