Cetirizine can interact with certain medications. Concurrent use with alcohol may increase drowsiness. Avoid combining cetirizine with other sedatives, including opioid painkillers or benzodiazepines, as this could significantly enhance sedative effects. This risk is particularly high for individuals already susceptible to drowsiness. The combined effect can impair judgment, coordination, and reaction time, leading to accidents.
Interactions with Specific Medications
MAO inhibitors (monoamine oxidase inhibitors) can potentially interact with cetirizine, though this is less commonly studied. Consult your doctor if you are taking an MAOI. Theophylline, used to treat breathing problems, may see its effects lessened by cetirizine. This necessitates close monitoring of theophylline levels if both medications are prescribed. Ketoconazole and other strong CYP3A4 inhibitors may increase cetirizine levels, potentially intensifying side effects. Discuss all your medications with your doctor or pharmacist to assess potential drug interactions before initiating or changing your treatment.
