Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil. Some medications can interact negatively with Sildenafil, potentially leading to adverse effects.
Specifically, be aware of potential interactions with:
- Nitrates: Combining Sildenafil with nitrates (found in some heart medications) can cause a dangerous drop in blood pressure. This combination is strictly contraindicated. Alpha-blockers: These medications, often used to treat high blood pressure or prostate problems, can also lower blood pressure, increasing the risk of hypotension when taken with Sildenafil. CYP3A4 inhibitors: These medications, including some antifungals (like ketoconazole) and macrolide antibiotics (like erythromycin), can increase Sildenafil levels in your blood, potentially intensifying side effects. CYP3A4 inducers: Conversely, medications like rifampin (an antibiotic) can decrease Sildenafil levels, reducing its effectiveness. HIV protease inhibitors: Some HIV medications can interact with Sildenafil, potentially affecting either drug’s efficacy.
Your doctor can help assess the risk of interactions and adjust dosages accordingly. Don’t hesitate to discuss any concerns you have regarding potential drug interactions before starting or continuing Sildenafil treatment.
This information is not exhaustive and does not substitute for professional medical advice. Always consult your physician or pharmacist for personalized guidance.
