Avoid taking risedronate with certain medications to prevent potential adverse effects. Specifically, nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, can increase the risk of stomach irritation and ulcers. Consult your doctor before combining risedronate with NSAIDs.
Risedronate absorption can be affected by other medications. For example, antacids containing aluminum, calcium, or magnesium, as well as sucralfate, can reduce risedronate’s effectiveness. Separate your risedronate dose from these medications by at least two hours.
Certain medications may increase your risk of side effects. For instance, concurrent use with corticosteroids can increase the risk of bone fractures. Always inform your doctor and pharmacist of all your medications, including over-the-counter drugs and herbal supplements.
| NSAIDs | Ibuprofen, Naproxen | Increased risk of gastrointestinal problems |
| Antacids | Aluminum-containing, Calcium-containing, Magnesium-containing antacids, Sucralfate | Reduced absorption of risedronate |
| Corticosteroids | Prednisone, Dexamethasone | Increased risk of fractures |
This information is not exhaustive. Always discuss potential drug interactions with your healthcare provider before starting or changing any medications.
